主持完成国家自然科学基金青年项目、面上项目及多项省部级课题。
1.国自然基金青年项目:肺腺癌新驱动突变基因IRS1的鉴定(81302001)
2.国自然基金面上项目:使用CRISPR/Cas9系统对肺鳞癌高频突变基因的筛选鉴定(81672304)
3.中国抗癌协会肺癌专业委员会《I-IIIB期非小细胞肺癌完全肿瘤切除术后辅助治疗指南》编者
4.中国抗癌协会科技奖一等奖《非小细胞肺癌围手术期精准治疗关键技术的推广与应用》获奖团队成员
部分文章如下:
(1) Li Chenguang; Gao Zhibo; Li Fei et al; Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell Carcinoma., Scientific Reports, 2015, 5: 14237-14237.
(2) Li Chenguang; Liu Hailin; Zhang Bin et al; Whole-exome sequencing identifies key mutated genes in T790M wildtype/cMET-unamplified lungadenocarcinoma with acquired resistance to first-generation EGFR tyrosine kinase inhibitors, Journal of Cancer Research and Clinical Oncology, 2018, 144(6): 1079-1086.
(3) Li, Chenguang; Sun, Yihua; Fang, Zhaoyuan et al.Comprehensive Analysis of Epidermal Growth Factor Receptor Gene Status in Lung Adenocarcinoma, JOURNAL OF THORACIC
ONCOLOGY, 2011, 6(6): 1016-1021.
(4) Wang Rui; Pan Yunjian; Li, Chenguang et al; The Use of Quantitative Real-Time Reverse Transcriptase PCR for 5 ' and 3 ' Portions of ALK Transcripts to Detect ALK Rearrangements in Lung Cancers, CLINICAL CANCER RESEARCH, 2012, 17(18): 4725-4732.
(5) Yihua Sun; Yan Ren; Zhaoyuan Fang; Chenguang Li et al; Lung adenocarcinoma from East Asian never smokers is a disease largely defined by targetable oncogenic mutant kinases, Journal of Clinical Oncology, 2010, 28(30): 4616-4620. |